Computational Neuroscience

A new dimension to access content of this website

Illustrated C. elegans worm with colored neural-network overlay — Rohit Ravi's connectomics + transcriptomics project

C. elegans Connectomics + Transcriptomics

Multi-modal analysis asking how much of local wiring in a small nervous system is determined by topology vs. gene expression.

Where is the blueprint in the C. elegans connectome — a decomposition of reproducible wiring into contact geometry, developmental timing, and a small transmitter bias, with the falsified hidden-code hypotheses

Where is the 'blueprint' in the C. elegans connectome?

A worm's genome is far too small to store its ~7,000 wiring connections one by one — yet the wiring is nearly the same in every animal. So where is the information that specifies it? This is the log of a systematic hunt: a dozen candidate 'hidden codes' tested and ruled out, and the surprisingly simple thing that was left standing.

C. elegans Tier4 substrate anatomy — 3D rendering of the whole-cell electrical model

Tier4 Substrate Anatomy — a whole-cell electrical substrate, rendered from code

An interactive 3D anatomy of the C. elegans Tier4 whole-cell electrical substrate. Every channel, receptor, pump, transporter, gap junction, and ion compartment actually present in the Brian2 model is rendered 1:1 from code with an honest ON / default-OFF / ORPHANED / NOT-INTEGRATED status.